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Mouse LAMP2/CD107b Recombinant Protein (RPES4504)

SKU:
RPES4504
Product Type:
Recombinant Protein
Species:
Mouse
€656
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Description

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Mouse LAMP2/CD107b Recombinant Protein

LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.

Product Name:Mouse LAMP2/CD107b Recombinant Protein (RPES4504)
Product Code:RPES4504
Size:50µg
Species:Mouse
Expressed Host:HEK293 Cells
Synonyms:CD107b,Lamp-2,Lamp-2a,Lamp-2b,Lamp-2c,LampII,LGP-B,Mac3
Accession:P17047-1
Sequence:Leu 26-Asn 379
Fusion tag:C-His
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the mouse LAMP2 (P17047-1) extracellular domain (Leu 26-Asn 379) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
Purity:> 97 % as determined by SDS-PAGE
Mol Mass:40.6 kDa
AP Mol Mass:70-80 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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