Testican3, also called SPOCK3, is a secreted protein and make up a family of extracellular heparan/chondroitin sulfate proteoglycans. It contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Testican3 contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. In addition to their presence in testis, testicans are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. It may participate in diverse steps of neurogenesis and Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. It also may interfere with tumor invasion.
Product Name:
Mouse Testican-3/SPOCK3 Recombinant Protein (RPES3150)
Product Code:
RPES3150
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Testican-3,Spock3
Accession:
Q8BKV0-1
Sequence:
Ala23-Ile436
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Testican-3 is produced by our Mammalian expression system and the target gene encoding Ala23-Ile436 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
47.9 kDa
AP Mol Mass:
58-60 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
