Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, which can be induced in CD4 T-cell by concanavalin-A. As a cell surface receptor, TREML2 may play a role in the innate and adaptive immune response. TREML2 also acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. It has shown that TREML2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.
Product Name:
Mouse TREML2/TLT2 Recombinant Protein (RPES3530)
Product Code:
RPES3530
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Trem-like transcript 2 protein, TLT-2, Triggering receptor expressed on myeloid cells-like protein 2, TREML2, TLT2
Accession:
Q2LA85
Sequence:
His25-Ala270
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Triggering Receptor Expressed on Myeloid Cells-like Protein 2 is produced by our Mammalian expression system and the target gene encoding His25-Ala270 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
28.4 kDa
AP Mol Mass:
58-62 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
