Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Product Name:
Mouse TROP2/TACSTD2 Recombinant Protein (RPES0325)
Product Code:
RPES0325
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Tumor-associated calcium signal transducer 2,Tacstd2,Trop2,Cell surface glycoprotein Trop-2, TROP-2,C80403,EGP-1,GA733-1,Ly97
Accession:
Q8BGV3
Sequence:
Gln25-Gly270
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse TROP2 is produced by our Mammalian expression system and the target gene encoding Gln25-Gly270 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
28.8 kDa
AP Mol Mass:
38-55 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
