The Recombinant Notch1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110681) against Notch1. This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HEK293. The target is localized to the membranous.
Product Name:
Recombinant Notch1 Monoclonal Antibody
SKU:
AGEL5990
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Activated NOTCH, Activated NOTCH1, AOS, AOS5, AOVD, AOVD1, hN1, Neurogenic locus Notch homolog protein, Neurogenic locus Notch homolog protein 1, NICD, NOTC, NOTC1, notch 1, Notch 1 intracellular domain, Notch homolog 1 translocation associated (Drosophila), Notch-1, NOTCH1, TAN, TAN1, Translocation-associated notch protein TAN, Translocation-associated notch protein TAN-1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Notch1 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110681
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Notch1
Conjugation:
Unconjugated
Observed MW:
120 kDa
Calculated MW:
273 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P46531
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.