The Recombinant p38 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C733266) against p38. MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation. It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Rat and Hamster samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Jurkat, C6, CHO-K1, Hela. The target is localized to the Cytoplasm. Nucleus.