The Recombinant p53 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C373378) against p53. TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IF applications. It has been validated by WB analysis of Jurkat and IF analysis of MCF-7. The target is localized to the cytoplasm, cytoplasm, nucleus, Nucleus>PML body, endoplasmic reticulum, Interaction with BANP promotes nuclear localization, Recruited into PML bodies together with CHEK2, nucleus, cytoplasm, localized in both nucleus and cytoplasm in most cells, in some cells, forms foci in the nucleus that are different from nucleoli, nucleus, cytoplasm, localized in the nucleus in most cells but found in the cytoplasm in some cells, nucleus, cytoplasm, localized mainly in the nucleus with minor staining in the cytoplasm, nucleus, cytoplasm, Predominantly nuclear but localizes to the cytoplasm when expressed with isoform 4 and Nucleus, cytoplasm, predominantly nuclear but translocates to the cytoplasm following cell stress.
Product Name:
Recombinant p53 Monoclonal Antibody
SKU:
AGEL8683
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Antigen NY-CO-13, BCC7, Cellular tumor antigen p53, FLJ92943, LFS1, Mutant tumor protein 53, P53, p53 tumor suppressor, Phosphoprotein p53, Tp53, Transformation related protein 53, TRP53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53