The Recombinant PCSK9 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131579) against PCSK9. PCSK9, also named as NARC1 and PC9, belongs to the peptidase S8 family. PCSK9 is expressed and secreted by several tissues but principally by the liver, small intestines, and kidney. It may be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of F9, SH-SY5Y, BxPC-3, BRL. The target is localized to the secreted.