The Recombinant PD L2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C733381) against PD L2. Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by thePDCD1LG2 gene.PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of K562, C6. The target is localized to the secreted, Cell membrane and Endomembrane system.