The Recombinant Phospho-DRP1 (Ser616) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170944) against DRP1 (Ser616). This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse, Rat and Bovine samples.
This antibody is suitable for WB, IF and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the cytoplasm.
DLP, DLP1, DNM1L, Dnm1p/Vps1p-like protein, Dnm1p/Vps1p-like protein (DVLP), dnml1, DRP, DRP1, DVLP, DYMPLE, dynamin 1 like, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin family member proline-rich carboxyl-terminal domain less (Dymple), Dynamin like protein, Dynamin related protein 1, Dynamin-1-like protein, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, Dynamin-related protein 1, DYNIV 11, EMPF, EMPF1, FLJ41912, HDYNIV, VPS1
Reactivity:
Human, Mouse, Rat, Bovine
Immunogen:
A synthetic peptide corresponding to residues around (Ser616) of Human Phospho-DRP1
Applications:
WBIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C170944
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
DRP1 (Ser616)
Conjugation:
Unconjugated
Observed MW:
82 kDa
Calculated MW:
82 kDa
Recommended Dilution:
WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
O00429
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with Recombinant Phospho-DRP1 (Ser616) Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: Hela whole cell lysate. Observed-MW:82 kDa Calculated-MW:82 kDa