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Recombinant Phospho-mTOR (Ser2448) Monoclonal Antibody (AGEL5422)

Datasheet MSDS
SKU AGEL5422
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110103
Conjugate Unconjugated
€409 - €559

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Description

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Recombinant Phospho-mTOR (Ser2448) Monoclonal Antibody

The Recombinant Phospho-mTOR (Ser2448) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110103) against mTOR (Ser2448). The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of A431, NIH/3T3 and IF analysis of HEK293.

Product Name:Recombinant Phospho-mTOR (Ser2448) Monoclonal Antibody
SKU:AGEL5422
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1), FK506 binding protein 12 rapamycin associated protein 1, FK506 binding protein 12 rapamycin associated protein 2, FK506 binding protein 12 rapamycin complex associated protein 1, FK506 binding protein 12-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP rapamycin associated protein, FKBP12 rapamycin complex associated protein, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FLJ44809, FRAP, FRAP1, FRAP2, Mammalian target of rapamycin, Mechanistic target of rapamycin, mTOR, OTTHUMP00000001983, RAFT, RAFT1, Rapamycin and FKBP12 target 1, Rapamycin associated protein FRAP2, Rapamycin target protein, Rapamycin target protein 1, RAPT, RAPT1, Serine/threonine-protein kinase mTOR, SKS
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide corresponding to the residues around Ser2448 of Human Phospho-mTOR
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C110103
Host:Rabbit
Isotype:Rabbit IgG
Target:mTOR (Ser2448)
Conjugation:Unconjugated
Observed MW:250 kDa
Calculated MW:289 kDa
Recommended Dilution:IHC 1:500-2000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:P42345, Q9JLN9, P42346
Purification:Protein A
Concentration:1 mg/mL
Buffer:0.2 µm filtered solution in PBS
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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