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Recombinant Phospho-PTEN (Ser380) Monoclonal Antibody (RMEA0121)

Datasheet MSDS
SKU RMEA0121
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C130107
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant Phospho-PTEN (Ser380) Monoclonal Antibody

The Recombinant Phospho-PTEN (Ser380) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C130107) against PTEN (Ser380). This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of MCF-7, HeLa, 293T, NIH/3T3, Mouse brain, Mouse kindey, Mouse liver, PC-12, Rat brain, Rat kidney, Rat liver. The target is localized to the cytoplasm, nucleus.

Product Name:Recombinant Phospho-PTEN (Ser380) Monoclonal Antibody
SKU:RMEA0121
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:10q23del, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, BZS, CWS, CWS1, DEC, GLM, GLM2, MGC11227, MHAM, MMAC, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, Phosphatase and tensin like protein, Phosphatidylinositol 3, PTEN, PTEN1, PTENbeta, TEP, TEP1
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic phosphopeptide corresponding to residues around Ser380 of the Human Phospho-PTEN
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C130107
Host:Rabbit
Isotype:Rabbit IgG
Target:PTEN (Ser380)
Conjugation:Unconjugated
Observed MW:54 kDa
Calculated MW:47 kDa
Recommended Dilution:WB 1:1000
UniProt:P60484
Purification:Protein A
Concentration:1 mg/mL
Buffer:0.2 µm filtered solution in PBS
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Product ImageWestern blot analysis of MCF-7,HeLa, 293T,NIH/3T3,Mouse brain,Mouse kindey,Mouse liver,PC- 12,Rat brain,Rat kidney and Rat liver cell lysates using Phospho-PTEN (Ser380) Antibody (RMEA0121) at a dilution of 1:1000. Observed-MW:54 kDa Calculated-MW:47 kDa
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