Recombinant PI3 Kinase Class 3 Monoclonal Antibody
The Recombinant PI3 Kinase Class 3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110265) against PI3 Kinase Class 3. ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate., cofactor:Manganese., Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes., similarity:Belongs to the PI3/PI4-kinase family., similarity:Contains 1 PI3K/PI4K domain., subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of Mouse brain, Rat brain. The target is localized to the midbody, late endosome, cytoplasmic vesicle, autophagosome, As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (PubMed:14617358). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity).
Product Name:
Recombinant PI3 Kinase Class 3 Monoclonal Antibody
SKU:
AGEL5584
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
hVps, hVps34, MGC61518, Phosphatidylinositol 3 kinase catalytic subunit type 3, Phosphatidylinositol 3 kinase class 3, Phosphatidylinositol 3 kinase p100 subunit, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide 3 kinase class 3, Phosphoinositide-3-kinase class 3, PI 3 Kinase Class 3, PI3 kinase type 3, PI3-kinase type 3, PI3K type 3, PIK3C, PIK3C3, PK3C3, PtdIns 3 kinase type 3, PtdIns-3-kinase type 3, VPS, Vps 34, VPS34
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human PI3 Kinase Class 3 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110265
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
PI3 Kinase Class 3
Conjugation:
Unconjugated
Observed MW:
102 kDa
Calculated MW:
102 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
Q8NEB9
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
