The Recombinant PLCG2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331514) against PLCG2. Phospholipase C-gamma2 (PLCG2) is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate to 1D-myo-inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor.IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Raji, Romas. The target is localized to the cytoplasm, cell membrane.
![Anti-PLCG2 [R42-7F-8] Monoclonal Antibody (AGMB03361)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/274650/680634/anti-plcg2-r42-7f-8-monoclonal-antibody-agmb03361__02805.1773042732.jpg?c=2 "Anti-PLCG2 [R42-7F-8] Monoclonal Antibody (AGMB03361)")
