The Recombinant PNKP Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321653) against PNKP. PNK (polynucleotide kinase) is a DNA repair enzyme that participates in single strand break repair and non-homologous end rejoining (NHEJ) for double strand breaks. PNK possesses a 5'-DNA kinase activity and a 3'-DNA phosphatase activity. It has three domains, a C terminal kinase domain, a central phosphatase domain, and an N-terminal forkhead associated (FHA) domain that is responsible for protein protein interactions. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa, PC-3 and IHC analysis of Human testis, Human thyroid cancer. The target is localized to the nucleus.
Product Name:
Recombinant PNKP Monoclonal Antibody
SKU:
AGEL6958
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
AOA, AOA4, EIEE, EIEE10, MCSZ, PNK, PNKP
Reactivity:
Human
Immunogen:
Peptide. This information is proprietary to PTMab.
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C321653
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
PNKP
Conjugation:
Unconjugated
Observed MW:
60 kDa
Calculated MW:
57 kDa
Recommended Dilution:
WB 1:2000; IHC 1:100
UniProt:
Q96T60
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
![Anti-PNKP [R03-0B8] Monoclonal Antibody (AGMB00363)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/271652/691655/anti-pnkp-r03-0b8-monoclonal-antibody-agmb00363__02358.1774503683.jpg?c=2 "Anti-PNKP [R03-0B8] Monoclonal Antibody (AGMB00363)")
