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Recombinant PPV Capsid protein VP1, N-His
Key Features

Recombinant PPV Capsid protein VP1, N-His (GXRP14098)

SKU GXRP14098
Product Type Recombinant Protein
Species PPV
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Recombinant PPV Capsid protein VP1, N-His

Recombinant PPV Capsid protein VP1, N-His is a recombinant protein expressed in E. coli, spanning Val191-Ile707, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Capsid protein VP1 is a ~80 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. For research use only.

The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s).

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