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Recombinant PRAME Monoclonal Antibody (AGEL6728)

Datasheet MSDS
SKU AGEL6728
Product Type Antibody
Reactivity Human
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C331423
Conjugate Unconjugated
$606 - $843

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Description

system_update_altDatasheetsystem_update_altMSDS

Recombinant PRAME Monoclonal Antibody

The Recombinant PRAME Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331423) against PRAME. This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of Ramos, K562, HeLa, A375. The target is localized to the membrane, cytoplasm, Golgi apparatus, nucleus.

Product Name:Recombinant PRAME Monoclonal Antibody
SKU:AGEL6728
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:4930534P07Rik, Cancer/testis antigen 130, CT130, MAPE, Melanoma antigen preferentially expressed in tumors, OIP, OIP 4, OIP-4, OIP4, OPA interacting protein 4, Opa interacting protein OIP4, OPA-interacting protein 4, PRAME, Preferentially expressed antigen in melanoma, Preferentially expressed antigen of melanoma, RP23-250F8.3
Reactivity:Human
Immunogen:Recombinant human PRAME fragment
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C331423
Host:Rabbit
Isotype:Rabbit IgG
Target:PRAME
Conjugation:Unconjugated
Observed MW:58 kDa
Calculated MW:58 kDa
Recommended Dilution:WB 1:500-1000
UniProt:P78395
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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