The Recombinant PRMT7 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C133386) against PRMT7. Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT). Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of K562, 3T3, Hela. The target is localized to the cytoplasm, cytosol. nucleus.
Product Name:
Recombinant PRMT7 Monoclonal Antibody
SKU:
AGEL8691
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
[Myelin basic protein]-arginine N-methyltransferase PRMT7, ANM7, FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Myelin basic protein arginine N methyltransferase, OTTHUMP00000174863, PRMT7, Protein arginine methyltransferase 7, Protein arginine N-, Protein arginine N-methyltransferase 7
![Anti-PRMT7 [R06-4F6] Monoclonal Antibody (AGMB00186)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/271475/693837/anti-prmt7-r06-4f6-monoclonal-antibody-agmb00186__36760.1774510542.jpg?c=2 "Anti-PRMT7 [R06-4F6] Monoclonal Antibody (AGMB00186)")
