The Recombinant PTEN Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110650) against PTEN. This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of MCF7 and IHC analysis of Rat panreas tissue, Human panreas tissue. The target is localized to the cytoplasm, nuclear.
Product Name:
Recombinant PTEN Monoclonal Antibody
SKU:
AGEL5961
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
10q23del, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, BZS, CWS, CWS1, DEC, GLM, GLM2, MGC11227, MHAM, MMAC, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, Phosphatase and tensin like protein, Phosphatidylinositol 3, PTEN, PTEN1, PTENbeta, TEP, TEP1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human PTEN protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110650
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
PTEN
Conjugation:
Unconjugated
Observed MW:
56 kDa
Calculated MW:
47 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P60484
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.