The Recombinant Rab 5A Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110628) against Rab 5A. Enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP., Required for the fusion of plasma membranes and early endosomes., similarity:Belongs to the small GTPase superfamily. Rab family., subcellular location:Enriched in stage I melanosomes., subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of HepG2 and IHC analysis of Human kidney tissue, Mouse kidney tissue. The target is localized to the cytoplasm, membrane.
Product Name:
Recombinant Rab 5A Monoclonal Antibody
SKU:
AGEL5940
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
RAB, RAB 5, RAB 5A, RAB5, RAB5A, RAB5A member RAS oncogene family, RAS associated protein RAB5A, Ras related protein Rab 5A, Ras-related protein Rab-5A
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Rab 5A protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110628
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Rab 5A
Conjugation:
Unconjugated
Observed MW:
24 kDa
Calculated MW:
24 kDa
Recommended Dilution:
IHC 1:1000-4000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P20339
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.