The Recombinant Raf-B Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110880) against Raf-B. This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by IHC analysis of Human prostate. The target is localized to the nucleus, cytoplasm, cell membrane, Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.
Product Name:
Recombinant Raf-B Monoclonal Antibody
SKU:
AGEL6186
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
94 kDa B raf protein, B raf 1, B Raf proto oncogene, B Raf proto oncogene serine threonine protein kinase, B RAF1, B-raf, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-RAF1, BRAF, BRAF 1, BRAF1, cRmil, FLJ95109, MGC126806, MGC138284, Murine sarcoma viral (v-raf) oncogene homolog B1, Murine sarcoma viral v raf oncogene homolog B1, NS7, Oncogen BRAF, oncogene BRAF1, p94, proto-oncogene B-Raf, Proto-oncogene c-Rmil, Raf-B, RAFB, RAFB 1, RAFB1, RMIL, serine/threonine kinase, serine/threonine-protein kinase B-raf, v raf murine sarcoma viral oncogene homolog B, v raf murine sarcoma viral oncogene homolog B1, v-Raf murine sarcoma viral oncogene homolog B1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Raf-B protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110880
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Raf-B
Conjugation:
Unconjugated
Recommended Dilution:
IHC 1:100-500; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P15056
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
