CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.
Product Name:
Rat CD81/TAPA Recombinant Protein (RPES3936)
Product Code:
RPES3936
Size:
100 µg
Species:
Rat
Expressed Host:
HEK293 Cells
Synonyms:
Tapa1
Accession:
NP_037219.1
Sequence:
Lys116-Lys201
Endotoxin:
<1.0 EU per µg protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the rat Cd81 (NP_037219.1) (Lys116-Lys201) was expressed with two additional amino acids (Gly & Pro) at the N-terminus.
Purity:
> 85 % as determined by SDS-PAGE
Mol Mass:
9.7 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
