The Recombinant RBBP4 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111271) against RBBP4. Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF, FC and IP applications. It has been validated by WB analysis of HeLa, CHO-K1, C6, Jurkat, Mouse spleen, IHC analysis of Human lung and IF analysis of HeLa. The target is localized to the nucleus.
![Anti-RBBP4 [R07-5D6] Monoclonal Antibody (AGMB00923)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/272212/694451/anti-rbbp4-r07-5d6-monoclonal-antibody-agmb00923__45154.1774512550.jpg?c=2 "Anti-RBBP4 [R07-5D6] Monoclonal Antibody (AGMB00923)")
