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Key Features

Recombinant RENT1 Monoclonal Antibody (AGEL8694)

Datasheet MSDS
SKU AGEL8694
Product Type Antibody
Reactivity Human
Applications WB, IHC-P, IF
Host Species Rabbit
Clonality Monoclonal
Clone C313389
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant RENT1 Monoclonal Antibody

The Recombinant RENT1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C313389) against RENT1. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of Jurkat, Hela and IF analysis of Human Cholangiocarcinoma, Hela. The target is localized to the Cytoplasm. Cytoplasm>P-body. Hyperphosphorylated form is targeted to the P-body, while unphosphorylated protein is distributed throughout the cytoplasm.

Product Name:Recombinant RENT1 Monoclonal Antibody
SKU:AGEL8694
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, FLJ43809, FLJ46894, HUPF 1, hUpf1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, Smg 2, Smg 2 homolog nonsens, Smg 2 homolog nonsense mediated mRNA decay factor, UP Frameshift 1, Up frameshift mutation 1 homolog, Up frameshift mutation 1 homolog (S. cerevisiae), Up frameshift suppressor 1 homolog, Up-frameshift suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, upf1, UPF1 regulator of nonsense transcripts homolog, UPF1 RNA helicase and ATPase, Yeast Upf1p homolog
Reactivity:Human
Immunogen:A synthetic peptide of human RENT1
Applications:WBIHC-PIF
Clonality:Recombinant Monoclonal
Clone No:C313389
Host:Rabbit
Isotype:Rabbit IgG
Target:RENT1
Conjugation:Unconjugated
Observed MW:124 kDa
Calculated MW:124 kDa
Recommended Dilution:WB 1:2000-3000; IHC 1:50-100; IF 1:50-100
UniProt:Q92900
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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