Rhesus macaque IFNAR1 Recombinant Protein (RPES3770)
- SKU:
- RPES3770
- Product Type:
- Recombinant Protein
- Species:
- Monkey
Frequently bought together:
Description
system_update_altDatasheet
Rhesus macaque IFNAR1 Recombinant Protein
Interferon?alpha/beta receptor 1 (IFN? alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
| Product Name: | Rhesus macaque IFNAR1 Recombinant Protein (RPES3770) |
| Product Code: | RPES3770 |
| Size: | 10µg |
| Species: | Rhesus macaque |
| Expressed Host: | Human Cells |
| Synonyms: | Alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta R1, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFNAR1, IFN-aR1, IFNBR, IFNbR1, IFN-bR1, IFN-R-1 |
| Accession: | H9FTY3 |
| Sequence: | Ala25-Lys437 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Rhesus macaque IFNAR1 is produced by our Mammalian expression system and the target gene encoding Ala25-Lys437 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 48.4 kDa |
| AP Mol Mass: | 70-120 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
