The Recombinant SIRT2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121349) against SIRT2. NAD-dependent protein deacetylase sirtuin-2 (SIRT2) is a NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. SIRT2 participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. SIRT2 plays a major role in the control of cell cycle progression and genomic stability. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HEK-293, SHSY-5Y, Mouse brain, Rat brain and IHC analysis of Human cerebellum. The target is localized to the cytoplasm, cytoskeleton.
Product Name:
Recombinant SIRT2 Monoclonal Antibody
SKU:
AGEL6654
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR, SIR2, SIR2-like protein 2, SIR2L, SIR2L2, SIRT, SIRT2, sirtuin, sirtuin 2, Sirtuin type 2
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human SIRT2 fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C121349
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SIRT2
Conjugation:
Unconjugated
Observed MW:
36, 43 kDa
Calculated MW:
43 kDa
Recommended Dilution:
WB 1:500-1000; IHC 1:50-100
UniProt:
Q8IXJ6
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.