The Recombinant Smad2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170637) against Smad2. The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IF, IP and ELISA applications. It has been validated by WB analysis of A549 treated with TPA of 48 hours. The target is localized to the cytoplasm, nuclear.
Product Name:
Recombinant Smad2 Monoclonal Antibody
SKU:
AGEL5949
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Drosophila, hMAD, hMAD-2, homolog of, hSMAD, hSMAD family member 2, hSMAD2, JV18, JV18-1, JV181, MAD, MAD homolog 2, MAD Related Protein 2, Mad-related protein 2, MADH, MADH2, MADR, MADR2, MGC22139, MGC34440, Mother against DPP homolog 2, Mothers against decapentaplegic, Mothers against decapentaplegic homolog 2, Mothers against DPP homolog 2, OTTHUMP00000163489, Sma and Mad related protein 2, Sma- and Mad-related protein 2 MAD, SMAD, SMAD 2, SMAD family member 2, Smad2
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Smad2 protein
Applications:
WBIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C170637
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Smad2
Conjugation:
Unconjugated
Observed MW:
58 kDa
Calculated MW:
58 kDa
Recommended Dilution:
WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q15796
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
