The Recombinant Smad4 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110451) against Smad4. This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of C6. The target is localized to the cytoplasm.
Product Name:
Recombinant Smad4 Monoclonal Antibody
SKU:
AGEL5768
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
(Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in Pancreatic Carcinoma 4, Deleted in pancreatic carcinoma locus 4, Deletion Target in Pancreatic Carcinoma, Deletion Target in Pancreatic Carcinoma 4, DPC, DPC 4, DPC4, Drosophila, homolog of, hSMAD, hSMAD4, JIP, MAD Homolog, MAD Homolog 4, MAD mothers against decapentaplegic Drosophila homolog 4, MAD mothers against decapentaplegic homolog 4, MADH, MADH 4, MADH4, Med, Medea, Mothers against decapentaplegic, Mothers Against Decapentaplegic Homolog, Mothers Against Decapentaplegic Homolog 4, Mothers Against DPP Homolog, Mothers Against DPP Homolog 4, MYHRS, OTTHUMP00000163548, SMA- and MAD-related protein 4, SMAD 4, SMAD family member, SMAD family member 4, SMAD mothers against DPP homolog 4, SMAD4
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Smad4 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110451
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Smad4
Conjugation:
Unconjugated
Observed MW:
60 kDa
Calculated MW:
60 kDa
Recommended Dilution:
IHC 1:2000-10000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q13485
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.