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Recombinant SMARCA2/BRM Monoclonal Antibody (AGEL6834)

Datasheet MSDS
SKU AGEL6834
Product Type Antibody
Reactivity Human, Mouse
Applications WB, IHC-P, ICC/IF, FC
Host Species Rabbit
Clonality Monoclonal
Clone C211529
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant SMARCA2/BRM Monoclonal Antibody

The Recombinant SMARCA2/BRM Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C211529) against SMARCA2/BRM. SMARCA2, also named as BRM, is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.

This antibody is suitable for WB, IHC-P, ICC/IF and FC applications. It has been validated by WB analysis of A549, HL-60, U-2 OS, IHC analysis of Human lung and IF analysis of 293, A549. The target is localized to the nucleus.

Product Name:Recombinant SMARCA2/BRM Monoclonal Antibody
SKU:AGEL6834
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ATP dependent helicase SMARCA2, ATP-dependent helicase SMARCA2, BAF190, BAF190B, BRG1-associated factor 190B, BRM, FLJ36757, Global transcription activator homologous sequence, hBRM, hSNF2a, MGC74511, Possible global transcription activator SNF2L2, Probable global transcription activator SNF2L2, Protein brahma homolog, SMARCA, SMARCA2, SMCA2, SNF2 alpha, SNF2 like 2, SNF2-alpha, SNF2/SWI2 like protein 2, SNF2A, SNF2L, SNF2L2, SNF2LA, Sth1p, Sucrose nonfermenting 2 like protein 2, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Reactivity:Human, Mouse
Immunogen:A synthetic peptide of human SMARCA2/BRM
Applications:WBIHC-PICC/IFFC
Clonality:Recombinant Monoclonal
Clone No:C211529
Host:Rabbit
Isotype:Rabbit IgG
Target:SMARCA2/BRM
Conjugation:Unconjugated
Observed MW:190 kDa
Calculated MW:181 kDa
Recommended Dilution:WB 1:1000; IHC-P 1:200-2000; ICC/IF 1:50; FCM 1:200-500
UniProt:P51531
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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