The Recombinant SOX17 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321581) against SOX17. SRY-related high mobility group box (SOX) proteins comprise a large family of widely conserved transcription factors. SOX proteins do not directly mediate transcription, but require binding partners that regulate their ability to mediate transcription of target genes that control cell fate determination and development. Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa (Low expression), SK-OV-3 and IHC analysis of Human seminoma. The target is localized to the nucleus.
Product Name:
Recombinant SOX17 Monoclonal Antibody
SKU:
AGEL6886
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
SOX, SOX17, VUR, VUR3
Reactivity:
Human
Immunogen:
Recombinant human SOX17 fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C321581
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SOX17
Conjugation:
Unconjugated
Observed MW:
55 kDa
Calculated MW:
55 kDa
Recommended Dilution:
WB 1:1000-2000; IHC 1:100-200
UniProt:
Q9H6I2
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Immunohistochemistry of paraffin-embedded Human seminoma using SOX17 Monoclonal Antibody at dilution of 1:200.
Western Blot with SOX17 Monoclonal Antibody at dilution of 1:1000. Lane 1: HeLa (Low expression), Lane 2: SK- OV-3 Observed-MW:55 kDa Calculated-MW:55 kDa