The Recombinant STAT3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110475) against Stat3. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of MCF7. The target is localized to the cytoplasm, nucleus.
Product Name:
Recombinant STAT3 Monoclonal Antibody
SKU:
AGEL5791
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
1110034C02Rik, Acute Phase Response Factor, Acute-Phase Response Factor, ADMIO, ADMIO1, APRF, AW109958, DNA binding protein APRF, FLJ20882, HIES, MGC16063, Signal Transducer and Activator of Transcription, Signal Transducer and Activator of Transcription 3, Signal transducer and activator of transcription 3 (acute phase response factor), STAT, STAT 3, STAT3
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human STAT3 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110475
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Stat3
Conjugation:
Unconjugated
Observed MW:
88 kDa
Calculated MW:
88 kDa
Recommended Dilution:
IHC 1:100-500; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P40763
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
