Description
Recombinant Synuclein-α Monoclonal Antibody
The Recombinant Synuclein-α Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110248) against Synuclein-α. Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse, Rat and C.elegans samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the cytoplasm, membrane, nucleus, cell junction, synapse, secreted, cell projection, axon, Membrane-bound in dopaminergic neurons (PubMed:15282274). Expressed and colocalized with SEPTIN4 in dopaminergic axon terminals, especially at the varicosities (by similarity).
| Product Name: | Recombinant Synuclein-α Monoclonal Antibody |
| SKU: | AGEL5567 |
| Size: | 50 µL, 100 µL |
| Antibody Type: | Recombinant Monoclonal Antibody |
| Synonyms: | alpha (non A4 component of amyloid precursor), Alpha synuclein, Alpha-synuclein, alphaSYN, aSYN, CD309, Fetal liver kinase, Fetal liver kinase 1, FLK-1, FLK1, isoform NACP140, KDR, Kinase insert domain receptor, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid, Non A4 component of amyloid precursor, Non-A beta component of AD amyloid, Non-A-beta component of alzheimers disease amyloid, Non-A4 component of amyloid, Non-A4 component of amyloid precursor, OTTHUMP00000218549, OTTHUMP00000218551, OTTHUMP00000218552, OTTHUMP00000218553, OTTHUMP00000218554, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease, Parkinson disease familial 1, PD1, precursor of, Protein-tyrosine kinase receptor flk, Protein-tyrosine kinase receptor flk-1, SNC-A, SNCA, Snca synuclein, SYN, Synuclein, Synuclein alpha, Synuclein alpha 140, SYUA, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, VEGFR, VEGFR-2, VEGFR2 |
| Reactivity: | Human, Mouse, Rat, C.elegans |
| Immunogen: | Recombinant Human Synuclein-α protein |
| Applications: | WBIHCIFIPELISA |
| Clonality: | Recombinant Monoclonal |
| Clone No: | C110248 |
| Host: | Rabbit |
| Isotype: | Rabbit IgG |
| Target: | Synuclein-α |
| Conjugation: | Unconjugated |
| Observed MW: | 18 kDa |
| Calculated MW: | 14 kDa |
| Recommended Dilution: | IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200 |
| UniProt: | P37840 |
| Purification: | Protein A |
| Concentration: | 0.2 mg/mL |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Storage: | Store at -20°C valid for 12 months. Avoid freeze / thaw cycles. |
