The Recombinant Tec Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111522) against Tec. Tec belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF and FC applications. It has been validated by WB analysis of K562, HeLa and IF analysis of HeLa. The target is localized to the cytoplasm, cell membrane, cytoskeleton.