The Recombinant Thrombospondin 1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C223398) against Thrombospondin 1. The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of MCF-7, 293T, C2C12 and IHC analysis of Human Cholangiocarcinoma. The target is localized to the endoplasmic reticulum, endoplasmic reticulum, endoplasmic reticulum lumen, sarcoplasmic reticulum, extracellular region or secreted, extracellular exosome, extracellular matrix, extracellular region, extracellular space, fibrinogen complex, Plasma Membrane, external side of plasma membrane, other locations: cell surface, platelet alpha granule, platelet alpha granule lumen, secretory granule.