The Recombinant Vimentin/VIM Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110078) against VIM. This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, ICC/IF and FC applications. It has been validated by WB analysis of HCT116, HeLa, Jurkat, A549, A431, NIH/3T3, Mouse brain, Mouse heart, PC12, Rat brain, Rat heart, IHC analysis of Human colon, Mouse colon, Rat colon and IF analysis of HeLa. The target is localized to the cytoplasm, nucleus matrix, cell membrane.