Retlirafusp Alfa (Research-Grade) is a research-grade biosimilar monoclonal antibody. It is a human IgG4-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays, in vivo research and Western blot. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Product Name:
Retlirafusp Alfa (Research-Grade)
SKU:
GXBS02023
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
B7 homolog 1
Isotype:
IgG4-kappa
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FCM, Functional assay, Research in vivo, WB
Synonyms:
SHR-1701
Recommended Dilutions:
WB: 1:500-1:2000
Biological Activity:
SHR-1701 (10 ug/mL) can inhibit TGF-β signaling pathway, activate PI3K/Akt/Erk signaling pathway, rescue lymphocytes and restore the anti-tumor function of peripheral blood CD8 + T cells in patients with lung cancer [1].
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4.
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Human alkaline phosphatase, tissue-nonspecific isozyme/AP-TNAP soluble fragment fused to a human immunoglobulin G4 heavy chain constant region fragment fused to a deca-aspartate peptide, disulfide bridged dimer.
