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Anti-RNF10 Antibody (CAB12296)

SKU:
CAB12296
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-RNF10 Antibody CAB12296
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-RNF10 Antibody CAB12296
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-RNF10 Antibody
Antibody SKU:CAB12296
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 552-811 of human RNF10 (NP_055683.3).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Raji, Mouse heart, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 552-811 of human RNF10 (NP_055683.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SMSE DVRQ RHRY LSHL PLTC EFSI CELA LQPP VVSK ETLE MFSD DIEK RKRQ RQKK AREE RRRE RRIE IEEN KKQG KYPE VHIP LENL QQFP AFNS YTCS SDSA LGPT STEG HGAL SISP LSRS PGSH ADFL LTPL SPTA SQGS PSFC VGSL EEDS PFPS FAQM LRVG KAKA DVWP KTAP KKDE NSLV PPAP VDSD GESD NSDR VPVP SFQN SFSQ AIEA AFMK LDTP ATSD PLSE EKGG KKRK KQKQ KLLF STSV VHTK
Gene ID:9921
Uniprot:Q8N5U6
Cellular Location:Cytoplasm, Nucleus
Calculated MW:89kDa/90kDa
Observed MW:100kDa
Synonyms:RNF10, RIE2
Background:The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the existence of multiple alternatively spliced transcript variants, however, their full length nature is not known.
UniProt Protein Function:RNF10: Transcriptional factor involved in the regulation of MAG expression. Participates in the peripheral nerve development and Schawnn cell differentiation. Belongs to the RNF10 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: cytoplasm; nucleus

Molecular Function:protein binding; ubiquitin-protein ligase activity

Biological Process: positive regulation of myelination; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein autoubiquitination

NCBI Summary:The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the existence of multiple alternatively spliced transcript variants, however, their full length nature is not known. [provided by RefSeq, Jul 2008]
UniProt Code:Q8N5U6
NCBI GenInfo Identifier:117949776
NCBI Gene ID:9921
NCBI Accession:Q8N5U6.2
UniProt Secondary Accession:Q8N5U6,Q92550, Q9NPP8, Q9ULW4,
UniProt Related Accession:Q8N5U6
Molecular Weight:90,497 Da
NCBI Full Name:RING finger protein 10
NCBI Synonym Full Names:ring finger protein 10
NCBI Official Symbol:RNF10  
NCBI Official Synonym Symbols:RIE2  
NCBI Protein Information:RING finger protein 10
UniProt Protein Name:RING finger protein 10
Protein Family:RING finger protein
UniProt Gene Name:RNF10  
UniProt Entry Name:RNF10_HUMAN
Anti-RNF10 Antibody (CAB12296)Western blot analysis of extracts of various cell lines, using RNF10 antibody (CAB12296) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Anti-RNF10 Antibody (CAB12296)Immunohistochemistry of paraffin-embedded rat spleen using RNF10 antibody (CAB12296) at dilution of 1:100 (40x lens).

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