Samrotamab Antibody (Samrotamab Vedotin ADC, Payload-Free) is a research-grade biosimilar monoclonal antibody targeting Leucine-rich repeat protein induced by beta-amyloid homolog. It is a humanized IgG1-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Supplied as the antibody component without the cytotoxic payload. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Leucine-rich repeat-containing protein 15 (LRRC15/LIB) is a ~64 kDa protein. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells.
