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Epigenetics and Nuclear Signaling Antibodies 5 Anti-SET1A Antibody CAB18231
Key Features

SET1A Rabbit Polyclonal Antibody (CAB18231)

Datasheet MSDS
SKU CAB18231
Product Type Antibody
Antibody Type Polyclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms Set1, EPEDD, KMT2F, Set1A, NEDSID, SET1A
Research Use Epigenetics and Nuclear Signaling
€96 - €370

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Description

system_update_altDatasheetsystem_update_altMSDS

SET1A Antibody (CAB18231)

The SET1A Antibody (CAB18231) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit polyclonal antibody is highly specific to SET1A and has been validated for use in Western blot applications, allowing for the detection and analysis of SET1A protein levels in various cell types.SET1A plays a critical role in controlling gene expression by methylating histone proteins, ultimately affecting the packaging of DNA and gene transcription. Dysregulation of SET1A has been linked to various diseases, including cancer and developmental disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:SET1A Antibody
SKU:CAB18231
Size:20μL, 100μL
Reactivity:Human, Mouse
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:Set1, EPEDD, KMT2F, Set1A, NEDSID, SET1A
Positive Sample:HeLa, Jurkat, HepG2, U-251MG, Mouse testis
Cellular Localization:Histone Methyltransferase Complex, Nuclear Speck, Nucleoplasm, Nucleus.
Calculated MW:186kDa
Observed MW:270kDa

The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.

Purification MethodAffinity purification
Gene ID9739
RRIDAB_2862007
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SET1A Rabbit pAb (CAB18231) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 5min.
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