null

SFPQ Antibody (PACO12142)

SKU:
PACO12142
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:SFPQ Antibody (PACO12142)
Antibody SKU:PACO12142
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human SFPQ
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated);SFPQ;POMP100;PSF ;
UniProt Protein Function:PSF: a proline-and glutamine-rich splicing factor. Essential pre-mRNA splicing factor required early in spliceosome formation. Seems to also bind DNA. The active complex is a heterotetramer of two 52 kDa and two 100 kDa subunits. Reported to be a PKC-alpha-binding protein in the cell nucleus. Two alternatively spliced isoforms have been described.
UniProt Protein Details:

Protein type:RNA splicing; RNA-binding; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: nucleoplasm; nuclear matrix; cytoplasm; nucleus; paraspeckles; chromatin

Molecular Function:protein binding; histone deacetylase binding; nucleotide binding

Biological Process: alternative nuclear mRNA splicing, via spliceosome; transcription, DNA-dependent; RNA splicing; rhythmic process; negative regulation of circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; DNA repair; mRNA processing; negative regulation of transcription, DNA-dependent; regulation of circadian rhythm; DNA recombination

UniProt Code:P23246
NCBI GenInfo Identifier:1709851
NCBI Gene ID:6421
NCBI Accession:P23246.2
UniProt Secondary Accession:P23246,P30808, Q5SZ71,
UniProt Related Accession:P23246
Molecular Weight:Calculated MW: 72kDa/76kDaObserved MW: 115kDa
NCBI Full Name:Splicing factor, proline- and glutamine-rich
NCBI Synonym Full Names:splicing factor proline/glutamine-rich
NCBI Official Symbol:SFPQ  
NCBI Official Synonym Symbols:PSF; POMP100; PPP1R140  
NCBI Protein Information:splicing factor, proline- and glutamine-rich; hPOMp100; 100 kDa DNA-pairing protein; PTB-associated splicing factor; PTB-associated-splicing factor; DNA-binding p52/p100 complex, 100 kDa subunit; protein phosphatase 1, regulatory subunit 140; polypyrimidine tract binding protein associated; polypyrimidine tract-binding protein-associated splicing factor; polypyrimidine tract-binding protein-associated-splicing factor; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated)
UniProt Protein Name:Splicing factor, proline- and glutamine-rich
UniProt Synonym Protein Names:100 kDa DNA-pairing protein; hPOMp100; DNA-binding p52/p100 complex, 100 kDa subunit; Polypyrimidine tract-binding protein-associated-splicing factor; PSF; PTB-associated-splicing factor
Protein Family:Splicing factor
UniProt Gene Name:SFPQ  
UniProt Entry Name:SFPQ_HUMAN

Related Products