Siltuximab Non-Neutralizing Antibody (1A457) is a monoclonal anti-drug antibody (ADA) offered by Assay Genie for research investigating immunogenicity against Siltuximab. Raised in mouse, it is intended for the detection and characterisation of anti-Siltuximab antibody responses and has been supplied for use in ELISA.
Anti-drug antibodies are a central readout in biotherapeutic development, where immunogenicity against a molecule such as Siltuximab can alter clearance, exposure and clinical response. This clone is characterised as non-neutralizing, binding Siltuximab without blocking its target interaction, which makes it suited to total-ADA and bridging assay formats. Supplied in 50 ?g, 100 ?g. For research use only; not for diagnostic or therapeutic procedures.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Format:
Liquid
Applications:
ELISA
Antibody Isotype:
IgG2a
Purity:
>95% as determined by SDS-PAGE.
Purification:
Protein A/G purified from cell culture supernatant.
