The SLC25A20 Antibody (CAB6880) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and has been rigorously validated for use in Western blot applications, providing reliable detection of SLC25A20 in human samples.SLC25A20 is a crucial mitochondrial protein involved in the transport of acylcarnitines across the inner mitochondrial membrane, playing a key role in fatty acid metabolism and energy production. Dysregulation of SLC25A20 has been linked to various metabolic disorders, making it a promising target for research in the fields of metabolism, bioenergetics, and mitochondrial diseases.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
SLC25A20 Antibody
SKU:
CAB6880
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
Purification Method
Affinity purification
Gene ID
788
RRID
AB_2767440
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SLC25A20 Rabbit pAb (CAB6880) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Immunofluorescence analysis of HeLa cells using SLC25A20 Rabbit pAb (CAB6880). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
