The SLC34A2 Antibody (CAB9460) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in Western blot and immunohistochemistry applications. It binds specifically to the SLC34A2 protein, allowing for the detection and analysis of its expression in various cell types and tissues.SLC34A2, also known as sodium-dependent phosphate transporter 2A, plays a crucial role in phosphate uptake and maintenance of phosphate levels in the body. Dysregulation of SLC34A2 has been linked to lung diseases such as pulmonary alveolar microlithiasis and pulmonary fibrosis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SLC34A2 Antibody
SKU:
CAB9460
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PULAM, NPTIIb, NaPi2b, NAPI-3B, NAPI-IIb, SLC34A2
Positive Sample:
A-549, 293T, HT-29, MCF7, Mouse small intestine, Rat lung
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
76kDa
Observed MW:
76kDa
The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
10568
RRID
AB_2772272
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SLC34A2 Rabbit pAb (CAB9460) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
