The SLC4A8 Polyclonal Antibody (CAB14825) is a valuable tool for researchers studying SLC4A8, a membrane transporter protein involved in ion transport and pH regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SLC4A8 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential component for studies in physiology, cell biology, and disease mechanisms.SLC4A8 plays a crucial role in maintaining cellular pH balance and ion homeostasis, making it a key player in physiological processes such as renal function, acid-base regulation, and neuronal excitability.
Dysregulation of SLC4A8 has been implicated in various diseases, including kidney disorders, neurological conditions, and cancer. By studying the function and regulation of SLC4A8, researchers can gain insights into disease mechanisms and potentially identify new therapeutic targets for these conditions.Overall, the SLC4A8 Polyclonal Antibody (CAB14825) is a valuable tool for researchers seeking to elucidate the role of SLC4A8 in health and disease, providing an opportunity to advance our understanding of ion transport mechanisms and uncover novel therapeutic strategies.
Product Name:
SLC4A8 Rabbit Polyclonal Antibody
SKU:
CAB14825
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human SLC4A8 (NP_001035049.1).
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9498
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC4A8 Rabbit pAb (CAB14825) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
