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Cell Biology Antibodies 8 Anti-SMARCA5 Antibody CAB2000
Key Features

SMARCA5/SNF2H Rabbit Polyclonal Antibody (CAB2000)

Datasheet MSDS
SKU CAB2000
Product Type Antibody
Antibody Type Polyclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms ISWI, SNF2H, hISWI, hSNF2H, WCRF135, SMARCA5/SNF2H
Research Use Cell Biology
€96 - €370

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Description

system_update_altDatasheetsystem_update_altMSDS

SMARCA5/SNF2H Antibody (CAB2000)

The SMARCA5/SNF2H Antibody (CAB2000) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting SMARCA5 in human samples, making it suitable for Western blot analysis.SMARCA5, also known as SNF2H, is essential for the proper functioning of the SWI/SNF complex, which plays a critical role in chromatin remodeling and gene expression. Dysregulation of SMARCA5 has been implicated in various diseases, including cancer, developmental disorders, and neurological conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:SMARCA5/SNF2H Antibody
SKU:CAB2000
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ELFA HFIQ PAAQ KTPT SPLK MKPG RPRI KKDE KQNL LSVG DYRH RRTE QEED EELL TESS KATN VCTR FEDS PSYV KWGK LRDY QVRG LNWL ISLY ENGI NGIL ADEM GLGK TLQT ISLL GYMK HYRN IPGP HMVL VPKS TLHN WMSE FKRW VPTL RSVC LIGD KEQR AAFV RDVL LPGE WDVC VTSY EMLI KEKS VFKK FNWR YLVI DEAH RIKN EKSK LSEI VREF KTTN RLLL TGTP LQNN LHEL WSLL NFLL PDVF NSAD DFDS WFDT NNCL GDQK LVER LHMV LRPF LLRR IKAD V
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ISWI, SNF2H, hISWI, hSNF2H, WCRF135, SMARCA5/SNF2H
Positive Sample:PC-3, H460, 293T, HepG2, SH-SY5Y, Mouse spleen, Mouse brain, Mouse testis
Cellular Localization:Nucleus.
Calculated MW:122kDa
Observed MW:125kDa

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.

Purification MethodAffinity purification
Gene ID8467
RRIDAB_2764024
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using SMARCA5/SNF2H Rabbit pAb (CAB2000) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 2min.
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