The SNX22 Polyclonal Antibody (PAC031800) is a valuable tool for researchers studying SNX22, a member of the sorting nexin (SNX) family of proteins involved in intracellular protein trafficking and sorting. This antibody is generated in rabbits and is highly specific for human samples, making it ideal for a variety of research applications.SNX22 is known to play a role in endocytosis and protein transport within cells, making it a key player in maintaining cellular homeostasis. By targeting SNX22 with this antibody, researchers can gain valuable insights into its function and mechanisms of action in various cell types.
This antibody is validated for use in Western blot applications, allowing for the detection and analysis of SNX22 protein levels.The study of SNX22 is important for understanding its role in cellular processes such as protein sorting, receptor internalization, and organelle function. By investigating SNX22 using this antibody, researchers can further their understanding of intracellular protein trafficking and potentially uncover new therapeutic targets for diseases involving dysregulated cellular pathways.
Antibody Name:
SNX22 Antibody (PACO31800)
Antibody SKU:
PACO31800
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Sorting nexin-22 protein (1-120AA)
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO31800 at dilution of 1:100.
Background:
May be involved in several stages of intracellular trafficking (By similarity). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Synonyms:
Sorting nexin-22, SNX22
UniProt Protein Function:
SNX22: May be involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). Belongs to the sorting nexin family.Protein type: VesicleChromosomal Location of Human Ortholog: 15q22.31Cellular Component: cytoplasmic vesicle membraneMolecular Function: phosphoinositide bindingBiological Process: protein transport
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a sorting nexin that is found in the cytoplasm, where it interacts with membrane-bound phosphatidylinositol 3-phosphate. The encoded protein may play a role in intracellular trafficking. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]