Description
Staphylococcus aureus fnbA Recombinant Protein (C-His)
Staphylococcus aureus fnbA Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Ala189-Ala505, with a C-terminal His tag. Predicted molecular weight: 37.80 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fibronectin-binding protein A (fnbA) is a ~111 kDa protein. Possesses multiple, substituting fibronectin (Fn) binding regions, each capable of conferring adherence to both soluble and immobilized forms of Fn. For research use only.
This confers to S.aureus the ability to invade endothelial cells both in vivo and in vitro, without requiring additional factors, although in a slow and inefficient way through actin rearrangements in host cells. This invasion process is mediated by integrin alpha-5/beta-1. Promotes bacterial attachment to both soluble and immobilized forms of fibrinogen (Fg) by means of a unique binding site localized within the 17 C-terminal residues of the gamma-chain of human Fg. Both plasma proteins (Fn and Fg) function as a bridge between bacterium and host cell.
| Product Name: | Staphylococcus aureus fnbA Recombinant Protein (C-His) |
| SKU: | GXRP08685 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Staphylococcus aureus |
| Synonyms: | Fibronectin-binding protein A, FnbpA, fnbA |
| Tag: | C-His |
| Expression Host: | E. coli |
| Protein Length: | Ala189-Ala505 |
| Calculated MW: | 37.80 kDa |
| UniProt: | P14738 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
