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Key Features

Survivin Rabbit Monoclonal Antibody (CAB4838)

Datasheet MSDS
SKU CAB4838
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse, Rat
Host Species Rabbit
Synonyms API4, EPR-1, Survivin
Research Use Cell Death
$173 - $603

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Description

system_update_altDatasheetsystem_update_altMSDS

Survivin Monoclonal Antibody (CAB4838)

The Survivin Monoclonal Antibody (CAB4838) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity in detecting survivin in human samples, making it a reliable choice for Western blot applications. By targeting survivin, researchers can delve into its role in cancer biology, particularly in cell proliferation and survival pathways.Survivin is a member of the inhibitor of apoptosis (IAP) family, known for its dual function in promoting cell survival and inhibiting programmed cell death.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:Survivin Monoclonal Antibody
SKU:CAB4838
Size:20μL, 100μL
Reactivity:Mouse, Rat
Clone Number:ARC0259
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MGAP TLPP AWQP FLKD HRIS TFKN WPFL EGCA CTPE RMAE AGFI HCPT ENEP DLAQ CFFC FKEL EGWE PDDD PIEE HKKH SSGC AFLS VKKQ FEEL TLGE FLKL DRER AKNK IAKE TNNK KKEF EETA KKVR RAIE QLAA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:API4, EPR-1, Survivin
Positive Sample:Mouse spleen, Mouse thymus, Rat testis
Cellular Localization:Chromosome, Cytoplasm, Midbody, Nucleus, Centromere, Cytoskeleton, Kinetochore, Spindle.
Calculated MW:16kDa
Observed MW:16kDa

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID332
RRIDAB_2863357
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Survivin Rabbit mAb (CAB4838) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1min.
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