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Suvizumab Antibody - Bioactivity-binding
Key Features

Suvizumab Antibody (GXBS00501)

SKU GXBS00501
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human immunodeficiency virus type 1 (HIV-1)
Applications ELISA, FACS, Functional assay, Research in vivo
Isotype IgG1, kappa
$409 - $1,138

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Description

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Suvizumab Antibody

Suvizumab Antibody is a research-grade biosimilar monoclonal antibody targeting env/Env polyprotein. It is a humanized IgG1, kappa antibody. Reactivity: Human immunodeficiency virus type 1 (HIV-1). Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Envelope glycoprotein gp160 (Envpolyprotein) is a ~97 kDa protein. Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.

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