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SYN-005-1B7 Antibody - SDS-PAGE
Key Features

SYN-005-1B7 Antibody (GXBS00545)

Datasheet MSDS
SKU GXBS00545
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Bordetella pertussis
Applications ELISA, FACS, Functional assay, Research in vivo
Isotype IgG1-kappa
€467 - €1,489

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Description

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SYN-005-1B7 Antibody

SYN-005-1B7 Antibody is a research-grade biosimilar monoclonal antibody targeting ptxAPTXS1. It is a humanized IgG1-kappa antibody. Reactivity: Bordetella pertussis. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Pertussis toxin subunit 1 (ptxAPTXS1) is a ~29 kDa protein. S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.

Product Name:SYN-005-1B7 Antibody
SKU:GXBS00545
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Target:ptxAPTXS1
Isotype:IgG1-kappa
Host Species:Human
Reactivity:Bordetella pertussis
Applications:ELISA, FACS, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:hu1B7, SYN-005, SYN-005-1B7
Purity:>95% purity as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:P04977
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